Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.86 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12001074 | 0.96 | ACACB (0.80) | ACACBPLK1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL256438 | 0.93 | ACACB (1.00) | ACACBPLK1 | |
| SCHEMBL12001190 | 0.82 | ACACB (0.68) | ACACBSMN1; SMN2MAPTGAA | |
| SCHEMBL256437 | 0.81 | ACACB (1.00) | ACACB | |
| SCHEMBL27254652 | 0.79 | ACACB (0.54) | ACACBSMN1; SMN2MAPTGAA | |
| SCHEMBL19079018 | 0.76 | PLK1 (0.69) | ACACBPLK1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL255804 | 0.76 | ACACB (0.81) | ACACBPLK1MAPTALDH1A1GAA | |
| SCHEMBL12001062 | 0.76 | ACACB (0.81) | ACACBPLK1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL12162492 | 0.74 | ACACB (0.52) | ACACBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24110662 | 0.74 | PLK1 (0.65) | ACACBPLK1KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |