Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19469482 | 0.77 | PTGS1 (0.49) | CYP1A2CYP2C19NPSR1MAPTTRPV1 | |
| SCHEMBL27254652 | 0.76 | ACACB (0.54) | CYP1A2CYP2C19MAPTRAB9ANPC1 | |
| SCHEMBL22839330 | 0.75 | POLB (0.44) | CYP1A2CYP2C19NPSR1MAPTTRPV1 | |
| SCHEMBL84835 | 0.75 | TRPV1 (0.49) | MAPTTRPV1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1900108 | 0.73 | GAA (0.57) | MAPTKDM4ETSHRGAALMNA | |
| SCHEMBL23052641 | 0.72 | MAPT (0.41) | CYP1A2CYP2C19NPSR1MAPTTRPV1 | |
| SCHEMBL14349287 | 0.72 | MAPT (0.41) | CYP1A2CYP2C19NPSR1MAPTTRPV1 | |
| SCHEMBL29337534 | 0.72 | MAPT (0.44) | CYP1A2CYP2C19NPSR1MAPTTRPV1 | |
| SCHEMBL5861384 | 0.71 | CYP1A2 (1.00) | CYP1A2CYP2C19NPSR1MAPTKDM4E | |
| SCHEMBL2607670 | 0.71 | MAPT (0.63) | CYP1A2CYP2C19NPSR1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |