Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18766184 | 1.00 | CACNA1C (0.41) | CACNA1CSCN5AKCNH2SMN1; SMN2MAPK1 | |
| SCHEMBL29675928 | 0.87 | KCNH2 (0.40) | SCN5AKCNH2SMN1; SMN2MAPK1GAA | |
| SCHEMBL29675844 | 0.84 | CACNA1C (0.42) | CACNA1CSCN5AKCNH2SMN1; SMN2MAPK1 | |
| SCHEMBL31592678 | 0.83 | GAA (0.46) | SMN1; SMN2MAPK1GAANPC1POLB | |
| SCHEMBL18765685 | 0.83 | GAA (0.46) | SMN1; SMN2MAPK1GAANPC1POLB | |
| SCHEMBL29676136 | 0.82 | MAPK1 (0.38) | SMN1; SMN2MAPK1GAANPC1POLB | |
| SCHEMBL23343856 | 0.80 | MAPK1 (0.40) | SMN1; SMN2MAPK1GAACNR1NPC1 | |
| Hydrochloric Acid SCHEMBL29676873 | 0.78 | MAPK1 (0.39) | SMN1; SMN2MAPK1GAACNR1NPC1 | |
| SCHEMBL29675600 | 0.77 | CYP3A4 (0.35) | CACNA1CSCN5AKCNH2SMN1; SMN2MAPK1 | |
| SCHEMBL29676835 | 0.76 | MAPK1 (0.38) | SMN1; SMN2MAPK1GAACNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |