SCHEMBL29676416

SCHEMBL29676416

CC(C)(NC(=O)CN1Cc2ncc(-c3nc(NC4CCOCC4)ncc3Cl)cc2C1=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18766148 1.00 MAPK1 (1.00) MAPK1
SCHEMBL18794041 0.90 MAPK1 (1.00) MAPK1
SCHEMBL29677016 0.86 MAPK1 (0.77) MAPK1
SCHEMBL18766108 0.86 MAPK1 (0.77) MAPK1
SCHEMBL18793360 0.85 MAPK1 (1.00) MAPK1
SCHEMBL30225881 0.85 MAPK1 (1.00) MAPK1
SCHEMBL30226031 0.84 MAPK1 (1.00) MAPK1
SCHEMBL18793971 0.84 MAPK1 (1.00) MAPK1
SCHEMBL18793676 0.84 MAPK1 (1.00) MAPK1
SCHEMBL30225916 0.84 MAPK1 (1.00) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365334-B1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS OTSUKA PHARMA CO LTD (JP) 2024-07-17 — — EP claimed
CN-108617166-B Protein kinase inhibitor benzolactam compounds 大冢制药株式会社 2022-05-17 — — CN claimed
CN-114948963-B Benzolactam compounds as protein kinase inhibitors 大冢制药株式会社 2025-05-27 — — CN disclosed
EP-3365334-B1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS OTSUKA PHARMA CO LTD (JP) 2024-07-17 — — EP disclosed
CN-114948963-A Protein kinase inhibitor benzolactam compounds 大冢制药株式会社 2022-08-30 — — CN disclosed
CN-108617166-B Protein kinase inhibitor benzolactam compounds 大冢制药株式会社 2022-05-17 — — CN disclosed
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