Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.48 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.48 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.48 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.48 |
| ▸ | CD69 | Q07108 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | LYN | P07948 | 3/20 | 0.41 |
| ▸ | BCR | P11274 | 3/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | ARAF | P10398 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.41 |
| ▸ | CSK | P41240 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794497 | 0.88 | BTK (0.65) | BTKIKBKETBK1MYLK4STK17A | |
| SCHEMBL16814232 | 0.88 | BTK (0.65) | BTKIKBKETBK1MYLK4STK17A | |
| SCHEMBL16794113 | 0.88 | BTK (0.65) | BTKIKBKETBK1MYLK4STK17A | |
| SCHEMBL29676473 | 0.88 | BTK (0.65) | BTKIKBKETBK1MYLK4STK17A | |
| SCHEMBL18170391 | 0.80 | BTK (0.70) | BTKIKBKETBK1MYLK4STK17A | |
| SCHEMBL16794252 | 0.78 | BTK (0.70) | BTKCD69 | |
| SCHEMBL16794059 | 0.78 | BTK (0.69) | BTKCD69 | |
| SCHEMBL16794456 | 0.77 | BTK (0.68) | BTKCD69 | |
| SCHEMBL29676669 | 0.77 | BTK (0.68) | BTKCD69 | |
| SCHEMBL16794360 | 0.77 | BTK (0.68) | BTKCD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2022-07-01 | — | — | CN | disclosed |