Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.56 |
| ▸ | CD69 | Q07108 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794208 | 1.00 | BTK (0.56) | BTKCD69KMT2ALMNATRPV1 | |
| SCHEMBL16794071 | 0.86 | BTK (0.43) | BTKCD69KMT2ALMNATRPV1 | |
| SCHEMBL29676706 | 0.84 | BTK (0.56) | BTKCD69KMT2ALMNATRPV1 | |
| SCHEMBL16794009 | 0.84 | BTK (0.56) | BTKCD69KMT2ALMNATRPV1 | |
| SCHEMBL20461142 | 0.84 | BTK (0.41) | BTKCD69KMT2ALMNATRPV1 | |
| SCHEMBL18170398 | 0.80 | USP30 (0.42) | BTKCD69 | |
| SCHEMBL20461139 | 0.79 | BTK (0.72) | BTKCD69 | |
| SCHEMBL29676448 | 0.79 | BTK (0.71) | BTKCD69 | |
| SCHEMBL16794214 | 0.79 | BTK (0.71) | BTKCD69 | |
| SCHEMBL20461159 | 0.78 | BTK (0.56) | BTKCD69KMT2ALMNACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2022-07-01 | — | — | CN | disclosed |