Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.60 |
| ▸ | GSK3B | P49841 | 7/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | WNT1 | P04628 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16793959 | 1.00 | BTK (0.60) | BTKGSK3BDYRK1AABL1WNT1 | |
| SCHEMBL22659930 | 0.95 | BTK (0.63) | BTKGSK3B | |
| SCHEMBL29533721 | 0.95 | BTK (0.63) | BTKGSK3B | |
| SCHEMBL16794047 | 0.83 | BTK (0.58) | BTK | |
| SCHEMBL16793934 | 0.82 | BTK (0.70) | BTK | |
| SCHEMBL25589530 | 0.80 | BTK (0.57) | BTK | |
| SCHEMBL20461065 | 0.79 | PIK3C3 (0.52) | GSK3BDYRK1AABL1WNT1 | |
| SCHEMBL22659803 | 0.79 | BTK (0.46) | BTKGSK3BABL1 | |
| SCHEMBL29533303 | 0.79 | BTK (0.46) | BTKGSK3BABL1 | |
| SCHEMBL16793958 | 0.78 | BTK (0.57) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2022-07-01 | — | — | CN | disclosed |