Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.76 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CD69 | Q07108 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.42 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.42 |
| ▸ | RIOK1 | Q9BRS2 | 1/20 | 0.42 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.42 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794463 | 1.00 | BTK (0.76) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL16794137 | 0.88 | BTK (0.76) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL16794161 | 0.87 | BTK (0.77) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL29676626 | 0.87 | BTK (0.77) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL20026920 | 0.86 | BTK (1.00) | BTK | |
| SCHEMBL16793893 | 0.85 | BTK (0.80) | BTK | |
| SCHEMBL16794215 | 0.85 | BTK (1.00) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL29676595 | 0.85 | BTK (1.00) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL16794144 | 0.84 | BTK (1.00) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL16794341 | 0.84 | BTK (0.77) | BTKJAK2CYP3A4HRH2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2022-07-01 | — | — | CN | disclosed |