Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26606982 | 0.82 | ADORA1 (0.49) | MAPTLMNARAB9AALDH1A1KDM4E | |
| SCHEMBL30573063 | 0.82 | ADORA1 (0.49) | MAPTLMNARAB9AALDH1A1KDM4E | |
| SCHEMBL21022103 | 0.78 | ADORA2A (0.43) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL18652678 | 0.76 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL1345243 | 0.71 | MAPK14 (0.38) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL16385603 | 0.69 | ESR2 (0.47) | MAPTALDH1A1KDM4E | |
| SCHEMBL2458840 | 0.69 | ADORA1 (0.49) | ALDH1A1KDM4EADORA2AADORA2B | |
| SCHEMBL13829027 | 0.69 | MAPK14 (0.40) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL16385601 | 0.67 | MAPT (0.44) | MAPTLMNARAB9ANPC1KDM4E | |
| SCHEMBL31665902 | 0.67 | MAPT (0.62) | MAPK14MAPK13MAPK12MAPK11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2022-07-01 | — | — | CN | disclosed |