Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.59 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.59 |
| ▸ | CDK7 | P50613 | 1/20 | 0.59 |
| ▸ | CD69 | Q07108 | 1/20 | 0.59 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.59 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.59 |
| ▸ | RIOK1 | Q9BRS2 | 1/20 | 0.59 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.59 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.59 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16793760 | 1.00 | BTK (0.59) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL20461055 | 0.87 | BTK (0.61) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL29676750 | 0.85 | BTK (0.69) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL16794224 | 0.85 | BTK (0.69) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL25584965 | 0.82 | BTK (0.59) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL29986746 | 0.81 | BTK (0.69) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL28881293 | 0.81 | BTK (0.69) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL18170395 | 0.80 | BTK (0.52) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL16794261 | 0.79 | BTK (0.53) | BTKAAK1JAK2CYP3A4HRH2 | |
| SCHEMBL18183954 | 0.78 | BTK (0.52) | BTKAAK1JAK2CYP3A4HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2022-07-01 | — | — | CN | disclosed |