Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 1.00 |
| ▸ | EGFR | P00533 | 10/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 10/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954011 | 1.00 | IGF1R (1.00) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2959327 | 0.93 | IGF1R (0.90) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2960930 | 0.91 | IGF1R (1.00) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2958312 | 0.91 | IGF1R (1.00) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2958314 | 0.91 | IGF1R (1.00) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2962503 | 0.90 | IGF1R (0.88) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2969343 | 0.90 | IGF1R (0.88) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2962500 | 0.90 | IGF1R (0.88) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2958334 | 0.89 | IGF1R (0.82) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2956092 | 0.89 | IGF1R (0.82) | IGF1REGFRERBB2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772231-B2 | Substituted pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors | ABBOTT LABORATORIES (US) | 2010-08-10 | — | — | US | claimed |