Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 1.00 |
| ▸ | KDR | P35968 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958164 | 1.00 | RET (1.00) | RETKDR | |
| SCHEMBL20535297 | 0.93 | RET (1.00) | RETKDR | |
| SCHEMBL25858094 | 0.93 | RET (0.89) | RETKDR | |
| SCHEMBL20534936 | 0.92 | RET (1.00) | RETKDR | |
| SCHEMBL20534715 | 0.92 | KDR (1.00) | RETKDR | |
| SCHEMBL20535546 | 0.89 | KDR (1.00) | RETKDR | |
| SCHEMBL20535280 | 0.84 | RET (1.00) | RETKDR | |
| SCHEMBL20535287 | 0.82 | RET (1.00) | RETKDR | |
| SCHEMBL21958128 | 0.82 | KDR (1.00) | RETKDR | |
| SCHEMBL29677844 | 0.82 | KDR (1.00) | RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110506043-B | Compounds useful as RET inhibitors | 癌症研究科技有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115785100-B | Compounds useful as RET inhibitors | 癌症研究科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-115785100-A | Compounds useful as RET inhibitors | 癌症研究科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-110506043-B | Compounds useful as RET inhibitors | 癌症研究科技有限公司 | 2022-11-01 | — | — | CN | disclosed |