SCHEMBL29678967

SCHEMBL29678967

O=C(O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)Cn1ccc(-c2ccc(NC(=O)CN3CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC3)cc2)n1)C(=O)O)C(=O)O

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29678811 0.88 FOLH1 (0.86) FOLH1
SCHEMBL29679234 0.88 FOLH1 (0.66) FOLH1
SCHEMBL29341571 0.87 FOLH1 (0.82) FOLH1
SCHEMBL29342047 0.87 FOLH1 (0.82) FOLH1
SCHEMBL29678828 0.85 FOLH1 (0.53) FOLH1
SCHEMBL25964173 0.84 FOLH1 (0.94) FOLH1
SCHEMBL29341585 0.84 FOLH1 (0.81) FOLH1
SCHEMBL16664910 0.82 FOLH1 (1.00) FOLH1
SCHEMBL24123222 0.82 FOLH1 (0.89) FOLH1
SCHEMBL24123210 0.82 FOLH1 (0.89) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003959-A1 TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER Bayer AS (NO) 2022-06-01 — — EP disclosed
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