SCHEMBL29679146

COc1c(C[C@@H](NC(=O)C2CCC(CNC(=O)CN3CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC3)CC2)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)ccc2ccccc12

nearest known ligand 0.83

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	FOLH1	Q04609	20/20	0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29679335	1.00	FOLH1 (0.83)	FOLH1
SCHEMBL16661545	0.91	FOLH1 (1.00)	FOLH1
SCHEMBL18059391	0.91	FOLH1 (1.00)	FOLH1
SCHEMBL29679452	0.87	FOLH1 (0.62)	FOLH1
SCHEMBL23979242	0.87	FOLH1 (0.84)	FOLH1
SCHEMBL29679060	0.86	FOLH1 (0.62)	FOLH1
SCHEMBL25964110	0.86	FOLH1 (0.86)	FOLH1
Vipivotide Tetraxetan SCHEMBL24729006	0.85	FOLH1 (1.00)	FOLH1
Vipivotide Tetraxetan SCHEMBL21316439	0.85	FOLH1 (1.00)	FOLH1
Vipivotide Tetraxetan SCHEMBL24729005	0.85	FOLH1 (1.00)	FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4003959-A1	TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER	Bayer AS (NO)	2022-06-01	—	—	EP	disclosed