SCHEMBL29679449

SCHEMBL29679449

Nc1ccc(CC(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)cc1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17705986 0.89 FOLH1 (0.76) FOLH1
SCHEMBL21249161 0.88 FOLH1 (0.74) FOLH1
SCHEMBL29338620 0.88 FOLH1 (0.74) FOLH1
SCHEMBL29340071 0.88 FOLH1 (0.74) FOLH1
SCHEMBL24123178 0.87 FOLH1 (0.73) FOLH1
SCHEMBL19303442 0.86 FOLH1 (0.72) FOLH1
SCHEMBL23252351 0.86 FOLH1 (0.69) FOLH1
SCHEMBL19089912 0.85 FOLH1 (0.65) FOLH1
SCHEMBL29679234 0.85 FOLH1 (0.66) FOLH1
SCHEMBL29678975 0.85 FOLH1 (0.71) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003959-A1 TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER Bayer AS (NO) 2022-06-01 — — EP disclosed
Send feedback