SCHEMBL29679665

SCHEMBL29679665

N#CN1CCCC(F)(c2nc3ccc(-c4ccn[nH]4)cc3[nH]2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 19/20 1.00
OTUD7B Q6GQQ9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20028862 1.00 USP30 (1.00) USP30OTUD7B
SCHEMBL29679389 0.82 USP30 (0.73) USP30OTUD7B
SCHEMBL20028898 0.82 USP30 (0.73) USP30OTUD7B
SCHEMBL20028861 0.78 USP30 (0.63) USP30
SCHEMBL20028881 0.70 USP30 (0.71) USP30OTUD7B
SCHEMBL20028876 0.70 USP30 (0.71) USP30OTUD7B
SCHEMBL20029003 0.69 USP30 (0.75) USP30
SCHEMBL20029037 0.69 USP30 (1.00) USP30
SCHEMBL20029004 0.69 USP30 (0.75) USP30
SCHEMBL29679746 0.68 USP30 (0.74) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790148-B Cyano-substituted heterocycles having USP30 inhibitor activity 特殊治疗有限公司 2022-06-07 CN claimed
CN-109790148-B Cyano-substituted heterocycles having USP30 inhibitor activity 特殊治疗有限公司 2022-06-07 CN disclosed