SCHEMBL29679679

SCHEMBL29679679

N#Cc1cc(-c2ccnc(-c3nnc([C@@]4(F)CCCN(C#N)C4)o3)c2)ccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20028903 1.00 USP30 (1.00) USP30
SCHEMBL29679749 1.00 USP30 (1.00) USP30
SCHEMBL20028868 0.93 USP30 (1.00) USP30
SCHEMBL29679448 0.93 USP30 (1.00) USP30
SCHEMBL29679860 0.93 USP30 (1.00) USP30
SCHEMBL21145365 0.92 USP30 (1.00) USP30
SCHEMBL20029000 0.92 USP30 (1.00) USP30
SCHEMBL21167242 0.89 USP30 (0.81) USP30
SCHEMBL21145395 0.85 USP30 (0.74) USP30
SCHEMBL20028852 0.81 USP30 (1.00) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790148-B Cyano-substituted heterocycles having USP30 inhibitor activity 特殊治疗有限公司 2022-06-07 CN claimed
CN-109790148-B Cyano-substituted heterocycles having USP30 inhibitor activity 特殊治疗有限公司 2022-06-07 CN disclosed