Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30922455 | 0.94 | KRAS (0.57) | KRAS | |
| SCHEMBL30706604 | 0.93 | KRAS (0.52) | KRAS | |
| SCHEMBL25337110 | 0.92 | KRAS (0.46) | KRAS | |
| SCHEMBL30922417 | 0.92 | KRAS (0.47) | KRAS | |
| SCHEMBL25335841 | 0.91 | KRAS (0.46) | KRAS | |
| SCHEMBL25334846 | 0.91 | KRAS (0.51) | KRAS | |
| SCHEMBL30539099 | 0.91 | KRAS (0.51) | KRAS | |
| SCHEMBL31029499 | 0.90 | KRAS (0.50) | KRAS | |
| SCHEMBL30706701 | 0.89 | KRAS (0.53) | KRAS | |
| SCHEMBL30922823 | 0.89 | KRAS (0.45) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540255-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244615-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
| EP-4262807-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022132200-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |