Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580784 | 0.93 | F2R (0.47) | GRIN2BF2RHTR2CCHRM4DRD2 | |
| SCHEMBL1580972 | 0.92 | F2R (0.52) | GRIN2BF2RHTR2CCHRM4DRD2 | |
| SCHEMBL27819410 | 0.91 | HCRTR2 (0.41) | GRIN2BF2RHTR2CCHRM4DRD2 | |
| SCHEMBL1580743 | 0.89 | F2R (0.40) | GRIN2BF2RHTR2CDRD2KIF11 | |
| SCHEMBL1580548 | 0.88 | F2R (0.52) | GRIN2BF2RKIF11 | |
| SCHEMBL1580501 | 0.87 | F2R (0.52) | F2RHTR2C | |
| SCHEMBL3161600 | 0.85 | F2R (0.51) | GRIN2BF2RCHRM4DRD2EPHX2 | |
| SCHEMBL27798015 | 0.84 | F2R (0.44) | GRIN2BF2RHTR2CCHRM4DRD2 | |
| SCHEMBL10233794 | 0.84 | NOTUM (0.45) | GRIN2BF2RHTR2CCHRM4DRD2 | |
| SCHEMBL1580896 | 0.83 | F2R (0.46) | GRIN2BF2RCHRM4DRD2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068214-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |