Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 11/20 | 0.61 |
| ▸ | PIM1 | P11309 | 9/20 | 0.61 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.61 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.59 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13852619 | 1.00 | PIM3 (0.61) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL14519078 | 0.82 | PIM3 (0.65) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL29954763 | 0.79 | TRIM24 (0.70) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL5438006 | 0.77 | TET2 (0.56) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL28578011 | 0.77 | TRIM24 (0.50) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL29639078 | 0.77 | TRIM24 (0.50) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL3594684 | 0.76 | CCNT1 (0.56) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL844764 | 0.76 | PIM3 (1.00) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL29394851 | 0.76 | PIM3 (1.00) | PIM3PIM1PIM2TRIM24TRIM33 | |
| SCHEMBL29955386 | 0.76 | TRIM24 (0.66) | PIM3PIM1PIM2TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2022133480-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |