Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28768935 | 1.00 | MAPT (0.63) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL397088 | 0.84 | MAPT (0.78) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2510105 | 0.84 | MCL1 (0.75) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL15645631 | 0.81 | MAPT (0.61) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2512100 | 0.81 | MAPT (0.69) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2506690 | 0.80 | MEN1 (0.71) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL19725538 | 0.79 | MAPT (0.59) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL27675259 | 0.79 | MAPT (0.62) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL8357237 | 0.79 | MAPT (0.62) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL4809452 | 0.79 | MAPT (0.64) | MAPTMEN1KMT2ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107459476-B | Anti-indoline cyclopropylamine compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-06-24 | — | — | CN | disclosed |