Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 20/20 | 0.44 |
| ▸ | CDK4 | P11802 | 19/20 | 0.44 |
| ▸ | CSF1R | P07333 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 9/20 | 0.41 |
| ▸ | CDK1 | P06493 | 4/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.40 |
| ▸ | CCND3 | P30281 | 10/20 | 0.39 |
| ▸ | CCND1 | P24385 | 6/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684582 | 0.94 | CDK6 (0.52) | CDK6CDK4CSF1RCDK2CDK1 | |
| SCHEMBL29684311 | 0.94 | CDK6 (0.52) | CDK6CDK4CSF1RCDK2CDK1 | |
| SCHEMBL24483282 | 0.87 | CDK6 (0.48) | CDK6CDK4CSF1RCDK2CDK7 | |
| SCHEMBL29684556 | 0.87 | CDK6 (0.48) | CDK6CDK4CSF1RCDK2CDK7 | |
| SCHEMBL29684367 | 0.87 | CDK6 (0.47) | CDK6CDK4CSF1RCDK2CDK1 | |
| SCHEMBL29684096 | 0.86 | CDK6 (0.52) | CDK6CDK4CSF1RCDK2CDK1 | |
| SCHEMBL29684601 | 0.85 | CDK6 (0.51) | CDK6CDK4CSF1RCDK2CDK1 | |
| SCHEMBL29684167 | 0.84 | CDK6 (0.46) | CDK6CDK4CSF1RCDK2CDK1 | |
| SCHEMBL24483429 | 0.82 | CDK6 (0.53) | CDK6CDK4CSF1RCDK2CDK1 | |
| SCHEMBL24483283 | 0.80 | CDK6 (0.56) | CDK6CDK4CSF1RCDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | claimed |
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |