Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 14/20 | 0.49 |
| ▸ | CDK4 | P11802 | 11/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | CCND3 | P30281 | 10/20 | 0.47 |
| ▸ | CDK2 | P24941 | 7/20 | 0.47 |
| ▸ | CDK1 | P06493 | 7/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 6/20 | 0.47 |
| ▸ | CCND1 | P24385 | 3/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CCNH | P51946 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24482656 | 1.00 | CDK6 (0.49) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL29684632 | 0.89 | DYRK2 (0.51) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL29683868 | 0.89 | DYRK2 (0.51) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL24482976 | 0.89 | DYRK2 (0.51) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL24483445 | 0.89 | DYRK2 (0.51) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL24483442 | 0.88 | CDK6 (0.52) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL29684493 | 0.88 | CDK6 (0.52) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL29684170 | 0.88 | CDK6 (0.50) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL29684518 | 0.88 | CDK6 (0.48) | CDK6CDK4DYRK2CSF1RPIK3CD | |
| SCHEMBL29684267 | 0.87 | DYRK2 (0.53) | CDK6CDK4DYRK2CSF1RPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | claimed |
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |