Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 20/20 | 0.51 |
| ▸ | CCND3 | P30281 | 15/20 | 0.51 |
| ▸ | CDK4 | P11802 | 15/20 | 0.51 |
| ▸ | CDK2 | P24941 | 10/20 | 0.51 |
| ▸ | CDK1 | P06493 | 9/20 | 0.51 |
| ▸ | CCNE2 | O96020 | 8/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.51 |
| ▸ | CCND1 | P24385 | 5/20 | 0.51 |
| ▸ | PIM1 | P11309 | 3/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684252 | 0.89 | CDK6 (0.51) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL24483417 | 0.89 | CDK6 (0.51) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL29684096 | 0.89 | CDK6 (0.52) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL29684593 | 0.88 | CDK6 (0.49) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL29684582 | 0.84 | CDK6 (0.52) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL29684311 | 0.84 | CDK6 (0.52) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL29684590 | 0.83 | CDK6 (0.49) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL29684097 | 0.82 | CDK6 (0.51) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL24483416 | 0.82 | CDK6 (0.51) | CDK6CCND3CDK4CDK2CDK1 | |
| SCHEMBL29684167 | 0.82 | CDK6 (0.46) | CDK6CCND3CDK4CDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |