Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 16/20 | 0.53 |
| ▸ | CDK4 | P11802 | 15/20 | 0.53 |
| ▸ | CSF1R | P07333 | 6/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.53 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.49 |
| ▸ | CCND1 | P24385 | 2/20 | 0.47 |
| ▸ | CCND3 | P30281 | 3/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | CDK9 | P50750 | 3/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CCNH | P51946 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CCNK | O75909 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24482800 | 1.00 | CDK6 (0.53) | CDK6CDK4CSF1RPIK3CDDYRK2 | |
| SCHEMBL24483230 | 0.92 | CDK6 (0.49) | CDK6CDK4CSF1RPIK3CDDYRK2 | |
| SCHEMBL29684434 | 0.92 | CDK6 (0.49) | CDK6CDK4CSF1RPIK3CDDYRK2 | |
| SCHEMBL29684228 | 0.90 | CDK6 (0.56) | CDK6CDK4CSF1RPIK3CDCCND1 | |
| SCHEMBL29684038 | 0.89 | CDK6 (0.51) | CDK6CDK4CSF1RPIK3CDDYRK2 | |
| SCHEMBL24482798 | 0.89 | CDK6 (0.51) | CDK6CDK4CSF1RPIK3CDDYRK2 | |
| SCHEMBL24483442 | 0.88 | CDK6 (0.52) | CDK6CDK4CSF1RPIK3CDDYRK2 | |
| SCHEMBL29684493 | 0.88 | CDK6 (0.52) | CDK6CDK4CSF1RPIK3CDDYRK2 | |
| SCHEMBL29684601 | 0.88 | CDK6 (0.51) | CDK6CDK4CSF1RPIK3CDCCND1 | |
| SCHEMBL24483429 | 0.88 | CDK6 (0.53) | CDK6CDK4CSF1RDYRK2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |