Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 18/20 | 0.63 |
| ▸ | CCND3 | P30281 | 13/20 | 0.63 |
| ▸ | CDK1 | P06493 | 9/20 | 0.63 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.63 |
| ▸ | CDK2 | P24941 | 6/20 | 0.63 |
| ▸ | PIM1 | P11309 | 5/20 | 0.63 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.63 |
| ▸ | CDK4 | P11802 | 16/20 | 0.61 |
| ▸ | CCND1 | P24385 | 5/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.61 |
| ▸ | CSF1R | P07333 | 2/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24482797 | 1.00 | CDK6 (0.63) | CDK6CCND3CDK1CCNA2CDK2 | |
| SCHEMBL24483439 | 0.94 | CDK6 (0.65) | CDK6CCND3CDK1CCNA2CDK2 | |
| SCHEMBL29684249 | 0.94 | CDK6 (0.65) | CDK6CCND3CDK1CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL29684104 | 0.93 | CDK6 (0.64) | CDK6CCND3CDK1CCNA2CDK2 | |
| SCHEMBL29684306 | 0.92 | CDK6 (0.63) | CDK6CCND3CDK1CCNA2CDK2 | |
| SCHEMBL24483233 | 0.92 | CDK6 (0.63) | CDK6CCND3CDK1CCNA2CDK2 | |
| SCHEMBL24482969 | 0.92 | CDK6 (0.64) | CDK6CCND3CDK1CCNA2CDK2 | |
| SCHEMBL29684371 | 0.92 | CDK6 (0.64) | CDK6CCND3CDK1CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL29683899 | 0.91 | CDK6 (0.64) | CDK6CCND3CDK1CCNA2CDK2 | |
| SCHEMBL24482799 | 0.91 | CDK6 (0.61) | CDK6CCND3CDK1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |