Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 16/20 | 0.41 |
| ▸ | JAK1 | P23458 | 13/20 | 0.41 |
| ▸ | TTK | P33981 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24497998 | 1.00 | TYK2 (0.41) | TYK2JAK1TTKKCNH2JAK2 | |
| SCHEMBL24498256 | 0.86 | JAK1 (0.44) | TYK2JAK1KCNH2JAK2JAK3 | |
| SCHEMBL29684955 | 0.86 | JAK1 (0.44) | TYK2JAK1KCNH2JAK2JAK3 | |
| SCHEMBL24497580 | 0.86 | TYK2 (0.51) | TYK2JAK1JAK2 | |
| SCHEMBL24497997 | 0.85 | TTK (0.39) | TYK2JAK1TTK | |
| SCHEMBL29686026 | 0.85 | TTK (0.39) | TYK2JAK1TTK | |
| SCHEMBL24498184 | 0.85 | JAK1 (0.51) | TYK2JAK1KCNH2JAK2JAK3 | |
| SCHEMBL24497575 | 0.84 | JAK1 (0.41) | TYK2JAK1KCNH2JAK2JAK3 | |
| SCHEMBL24497576 | 0.83 | JAK1 (0.42) | TYK2JAK1KCNH2JAK2JAK3 | |
| SCHEMBL29685149 | 0.83 | JAK1 (0.42) | TYK2JAK1KCNH2JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | claimed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | claimed |
| EP-4257587-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |