Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23274286 | 1.00 | STAT3 (0.40) | STAT3MAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL23274673 | 0.94 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL29684752 | 0.94 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL23274496 | 0.94 | STAT3 (0.39) | STAT3MAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL23274450 | 0.94 | STAT3 (0.39) | STAT3MAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL23274493 | 0.94 | SMN1; SMN2 (0.43) | STAT3MAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL29685287 | 0.93 | TP53 (0.40) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL23274620 | 0.93 | TP53 (0.40) | MAPTSMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL23275482 | 0.92 | STAT3 (0.40) | STAT3MAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL29685506 | 0.92 | STAT3 (0.40) | STAT3MAPTSMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114667282-B | Pyrimidine amide compounds and methods of treating cancer | 昊运股份有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-114667282-B | Pyrimidine amide compounds and methods of treating cancer | 昊运股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-4048656-A1 | PYRIMIDINE AMIDE COMPOUNDS AND USE THEREOF | Alphala Co., Ltd. (TW) | 2022-08-31 | — | — | EP | disclosed |
| CN-114667282-A | Pyrimidine amide compounds and methods of treating cancer | 昊运股份有限公司 | 2022-06-24 | — | — | CN | disclosed |