Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 6/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.34 |
| ▸ | NPM1 | P06748 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20093009 | 1.00 | TYK2 (0.42) | TYK2CYP19A1HDAC3HDAC1HDAC2 | |
| SCHEMBL20073548 | 0.94 | CYP19A1 (0.39) | TYK2CYP19A1HDAC3HDAC1HDAC2 | |
| SCHEMBL20150204 | 0.93 | CYP19A1 (0.43) | TYK2CYP19A1HDAC1HDAC2KMT2A | |
| SCHEMBL20150174 | 0.90 | TYK2 (0.46) | TYK2CYP19A1ALK | |
| SCHEMBL24498494 | 0.85 | HDAC1 (0.35) | TYK2HDAC3HDAC1HDAC2 | |
| SCHEMBL24498549 | 0.85 | CYP2C9 (0.35) | TYK2HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL29686947 | 0.85 | HDAC1 (0.35) | TYK2HDAC3HDAC1HDAC2 | |
| SCHEMBL20073547 | 0.83 | TYK2 (0.48) | TYK2CYP19A1 | |
| SCHEMBL24497510 | 0.83 | TYK2 (0.43) | TYK2CYP19A1ALKJAK2JAK3 | |
| SCHEMBL24498229 | 0.81 | TYK2 (0.40) | TYK2CYP19A1ALKNPM1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |