Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 17/20 | 0.47 |
| ▸ | JAK1 | P23458 | 11/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29686362 | 1.00 | TYK2 (0.47) | TYK2JAK1CYP2C19MAP2K1JAK2 | |
| SCHEMBL24497675 | 1.00 | TYK2 (0.47) | TYK2JAK1CYP2C19MAP2K1JAK2 | |
| SCHEMBL29686522 | 0.95 | TYK2 (0.46) | TYK2JAK1CYP2C19MAP2K1JAK2 | |
| SCHEMBL24498504 | 0.95 | TYK2 (0.46) | TYK2JAK1CYP2C19MAP2K1JAK2 | |
| SCHEMBL29686474 | 0.94 | TYK2 (0.54) | TYK2JAK1CYP2C19MAP2K1JAK2 | |
| SCHEMBL24498496 | 0.94 | TYK2 (0.54) | TYK2JAK1CYP2C19MAP2K1JAK2 | |
| SCHEMBL24497674 | 0.90 | TYK2 (0.54) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL29686389 | 0.90 | TYK2 (0.54) | TYK2JAK1CYP2C19JAK2KCNH2 | |
| SCHEMBL24899716 | 0.88 | TYK2 (0.54) | TYK2JAK1CYP2C19JAK2PDE4D | |
| SCHEMBL24498060 | 0.86 | TYK2 (0.49) | TYK2JAK1CYP2C19JAK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |