Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GRK6 | P43250 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26122504 | 1.00 | KAT2B (0.52) | KAT2BTSHRCYP3A4MAPTGRK6 | |
| SCHEMBL29739994 | 0.83 | MAPT (0.59) | TSHRMAPTALDH1A1LMNAPKM | |
| SCHEMBL26121230 | 0.83 | MAPT (0.59) | TSHRMAPTALDH1A1LMNAPKM | |
| SCHEMBL6859176 | 0.83 | ATM (0.49) | MAPTALDH1A1LMNAPKM | |
| SCHEMBL27183310 | 0.83 | TSHR (0.53) | KAT2BTSHRCYP3A4MAPTGRK6 | |
| SCHEMBL30873006 | 0.83 | TSHR (0.53) | KAT2BTSHRCYP3A4MAPTGRK6 | |
| SCHEMBL981242 | 0.79 | KAT2B (0.64) | KAT2BTSHRCYP3A4MAPTGRK6 | |
| SCHEMBL26118836 | 0.78 | TSHR (0.47) | KAT2BTSHRCYP3A4MAPTGRK6 | |
| SCHEMBL29686668 | 0.78 | TSHR (0.47) | KAT2BTSHRCYP3A4MAPTGRK6 | |
| SCHEMBL978709 | 0.76 | TSHR (0.62) | KAT2BTSHRCYP3A4MAPTGRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |