Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | MARK3 | P27448 | 1/20 | 0.54 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.54 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.54 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.54 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.54 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.54 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.54 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.54 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.54 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.54 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.54 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.54 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65092 | 0.90 | FGFR1 (0.54) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL64062 | 0.89 | FGFR1 (0.55) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL29687915 | 0.89 | FGFR1 (0.51) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL64325 | 0.89 | FGFR1 (0.53) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL65013 | 0.89 | FGFR1 (0.54) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL64111 | 0.88 | FGFR1 (0.56) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL29687913 | 0.87 | FGFR1 (0.50) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63434 | 0.87 | FGFR1 (0.51) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL64186 | 0.86 | FGFR1 (0.51) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL65501 | 0.86 | FGFR1 (0.54) | FGFR1NTRK1RETPDGFRBMARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220298143-A1 | Pyrazole Derivatives for FGFR Inhibitor and Preparation Method Thereof | ETERN BIOPHARMA (SHANGHAI) CO., LTD. (CN) | 2022-09-22 | — | — | US | disclosed |
| CN-114728910-A | Pyrazole derivatives for FGFR inhibitor and preparation method thereof | 上海奕拓医药科技有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-4023639-A1 | PYRAZOLE DERIVATIVE FOR FGFR INHIBITOR AND PREPARATION METHOD THEREFOR | Etern Biopharma (Shanghai) Co., Ltd. (CN) | 2022-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298143-A1 | Pyrazole Derivatives for FGFR Inhibitor and Preparation Method Thereof | FGFR1, FGFR2, FGFR3 | FGFR1 1/4885NTRK1 1338/4885RET 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.