Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135261 | 1.00 | PDE10A (0.41) | PDE10ACACNA2D1CACNA2D2ADRB1SMN1; SMN2 | |
| SCHEMBL1828990 | 0.81 | PDE10A (0.50) | PDE10AADRB1CHRNB2CHRNA4HRH4 | |
| SCHEMBL1830467 | 0.70 | SMO (0.70) | HTR2C | |
| SCHEMBL30040822 | 0.69 | HTR2C (0.53) | ADRB1CHRNB2CHRNA4HTR2C | |
| SCHEMBL9045898 | 0.69 | HTR2C (0.53) | ADRB1CHRNB2CHRNA4HTR2C | |
| Hydrochloric Acid SCHEMBL23932476 | 0.68 | HTR2C (0.51) | CHRNB2CHRNA4HTR2C | |
| Hydrochloric Acid SCHEMBL30041876 | 0.68 | HTR2C (0.51) | CHRNB2CHRNA4HTR2C | |
| SCHEMBL605163 | 0.68 | HRH4 (0.55) | PDE10AHRH4 | |
| SCHEMBL8339118 | 0.68 | BPTF (0.50) | PDE10AADRB1CHRNB2CHRNA4HTR2C | |
| SCHEMBL13931121 | 0.68 | HTR2C (0.41) | PDE10AADRB1CHRNB2CHRNA4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |