Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 9/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.55 |
| ▸ | TOP1 | P11387 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942287 | 1.00 | TOP2A (0.55) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL29689942 | 0.90 | TOP2A (0.54) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL29690315 | 0.90 | TOP2A (0.54) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL28942276 | 0.90 | TOP2A (0.54) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL28942265 | 0.90 | TOP2A (0.54) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL28942260 | 0.90 | CYP3A4 (0.49) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL29689771 | 0.89 | TOP2A (0.53) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL28942301 | 0.89 | TOP2A (0.53) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL29690159 | 0.87 | TOP2A (0.56) | TOP2ATOP2BTOP1CYP2C9CYP3A4 | |
| SCHEMBL28942268 | 0.87 | TOP2A (0.56) | TOP2ATOP2BTOP1CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539213-A | Fluoroquinolone compound and preparation method and application thereof | 广东工业大学 | 2022-05-27 | — | — | CN | claimed |
| CN-114539213-A | Fluoroquinolone compound and preparation method and application thereof | 广东工业大学 | 2022-05-27 | — | — | CN | disclosed |