Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 20/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.88 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.88 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.78 |
| ▸ | TSPO | P30536 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30608312 | 0.94 | P2RY14 (0.89) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL22996148 | 0.94 | P2RY14 (1.00) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL30195805 | 0.94 | P2RY14 (1.00) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL29691896 | 0.92 | P2RY14 (0.86) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL29691902 | 0.92 | P2RY14 (1.00) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL29691816 | 0.91 | P2RY14 (0.83) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL29691826 | 0.90 | P2RY14 (1.00) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL182551 | 0.88 | P2RY14 (0.78) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL29691872 | 0.88 | P2RY14 (1.00) | P2RY14OPRD1KCNH2TMEM97TSPO | |
| SCHEMBL29691891 | 0.88 | P2RY14 (1.00) | P2RY14OPRD1KCNH2TMEM97TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4277895-A1 | HETEROCYCLIC P2Y 14 RECEPTOR ANTAGONISTS | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2023-11-22 | — | — | EP | disclosed |
| CN-116964034-A | Heterocyclic ring P2Y 14 Receptor antagonists | 美国卫生和人力服务部 | 2023-10-27 | — | — | CN | disclosed |
| WO-2022155037-A1 | HETEROCYCLIC P2Y 14 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-07-21 | — | — | WO | disclosed |