SCHEMBL29696192

SCHEMBL29696192

CCCC[C@H](N)C(=O)NCCc1ccc(-c2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.87

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.87
DPP7 Q9UHL4 2/20 0.49
SPHK1 Q9NYA1 5/20 0.46
HDAC8 Q9BY41 2/20 0.45
MMP2 P08253 1/20 0.44
MMP3 P08254 1/20 0.44
RRM1 P23921 1/20 0.43
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
PLAAT3 P53816 1/20 0.42
PLAAT5 Q96KN8 1/20 0.42
PLAAT2 Q9NWW9 1/20 0.42
PLAAT4 Q9UL19 1/20 0.42
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
SPHK2 Q9NRA0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27212681 1.00 KCNH2 (0.87) KCNH2DPP7SPHK1HDAC8MMP2
Hydrochloric Acid SCHEMBL29385528 0.99 KCNH2 (0.87) KCNH2DPP7SPHK1HDAC8MMP2
SCHEMBL27212691 0.93 KCNH2 (1.00) KCNH2SPHK1HDAC8CA1CA2
SCHEMBL29696198 0.93 KCNH2 (1.00) KCNH2SPHK1HDAC8CA1CA2
Hydrochloric Acid SCHEMBL29385466 0.92 KCNH2 (1.00) KCNH2SPHK1HDAC8CA1CA2
SCHEMBL27212676 0.88 KCNH2 (0.68) KCNH2DPP7SPHK1CA1CA2
SCHEMBL29696205 0.88 KCNH2 (0.82) KCNH2HDAC8CA1CA2PLAAT3
SCHEMBL27212694 0.88 KCNH2 (0.82) KCNH2HDAC8CA1CA2PLAAT3
Hydrochloric Acid SCHEMBL29385897 0.87 KCNH2 (0.69) KCNH2DPP7SPHK1CA1CA2
Hydrochloric Acid SCHEMBL29386333 0.87 KCNH2 (0.83) KCNH2HDAC8CA1CA2PLAAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022139564-A1 NOVEL DERIVATIVE COMPOUND HAVING BIPHENYL GROUP INTRODUCED INTO AMINO-ALKANOIC ACID AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME (주)앰틱스바이오 2022-06-30 WO disclosed