Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925720 | 1.00 | KMT2A (0.40) | KMT2ALMNAVCPMAPK1KIF11 | |
| SCHEMBL22925719 | 0.88 | KMT2A (0.42) | KMT2AVCPKIF11DHODH | |
| SCHEMBL22925600 | 0.87 | TRPV1 (0.45) | VCPFLT1FLT4KDR | |
| SCHEMBL22925613 | 0.82 | TRPV1 (0.36) | KMT2AVCPKIF11KDM4EFLT1 | |
| SCHEMBL29696298 | 0.82 | TRPV1 (0.36) | KMT2AVCPKIF11KDM4EFLT1 | |
| SCHEMBL28733637 | 0.81 | KMT2A (0.40) | KMT2AVCPMAPK1KIF11KDM4E | |
| SCHEMBL22925928 | 0.81 | KMT2A (0.40) | KMT2AVCPMAPK1KIF11KDM4E | |
| SCHEMBL24636898 | 0.79 | SCN9A (0.36) | KMT2A | |
| SCHEMBL22925698 | 0.79 | SCN9A (0.36) | KMT2A | |
| SCHEMBL29620956 | 0.79 | SCN9A (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |