Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 16/20 | 0.70 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22933159 | 1.00 | CD38 (0.70) | CD38YTHDC1KLKB1ROCK2CYP3A4 | |
| SCHEMBL29696551 | 0.86 | CD38 (0.77) | CD38YTHDC1KLKB1ROCK2 | |
| SCHEMBL22936235 | 0.86 | CD38 (0.77) | CD38YTHDC1KLKB1ROCK2 | |
| SCHEMBL29494891 | 0.82 | CD38 (1.00) | CD38YTHDC1KLKB1 | |
| SCHEMBL22932675 | 0.82 | CD38 (1.00) | CD38YTHDC1KLKB1 | |
| SCHEMBL22932801 | 0.76 | CD38 (1.00) | CD38KLKB1ROCK2 | |
| SCHEMBL31484487 | 0.76 | CD38 (1.00) | CD38KLKB1ROCK2 | |
| SCHEMBL22946897 | 0.76 | CD38 (1.00) | CD38KLKB1 | |
| SCHEMBL30142564 | 0.76 | CD38 (1.00) | CD38KLKB1 | |
| SCHEMBL22936300 | 0.73 | CD38 (1.00) | CD38KLKB1ROCK2CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| EP-4003980-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | Ribon Therapeutics Inc. (US) | 2022-06-01 | — | — | EP | disclosed |