Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 8/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030053 | 1.00 | LIMK1 (0.39) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL23380783 | 0.98 | LIMK1 (0.38) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL20029897 | 0.98 | LIMK1 (0.39) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL20029855 | 0.98 | LIMK1 (0.39) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL23380777 | 0.97 | LIMK1 (0.37) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL22006598 | 0.97 | LIMK1 (0.41) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL22006907 | 0.96 | LIMK1 (0.38) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL22006505 | 0.95 | LIMK1 (0.39) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL20024188 | 0.95 | LIMK1 (0.37) | LIMK1ATMKDM4EL3MBTL1PIM1 | |
| SCHEMBL22006257 | 0.95 | LIMK1 (0.41) | LIMK1ATMKDM4EL3MBTL1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232137-A | Compound having diaza dibenzofuran or diaza dibenzothiophene structure | 默克专利有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115160329-A | Compounds having a structure of diaza-dibenzofuran or diaza-dibenzothiophene | 默克专利有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115160328-A | Compounds having a structure of diaza-dibenzofuran or diaza-dibenzothiophene | 默克专利有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-109689658-B | Compounds having a structure of diaza-dibenzofuran or diaza-dibenzothiophene | 默克专利有限公司 | 2022-07-26 | — | — | CN | disclosed |