Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 15/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22435395 | 1.00 | NR1H2 (0.45) | NR1H2GRM5ESR2POLB | |
| SCHEMBL24536068 | 0.93 | NR1H2 (0.41) | NR1H2GRM5ESR2POLB | |
| SCHEMBL30030794 | 0.89 | NR1H2 (0.44) | NR1H2GRM5ESR2POLB | |
| SCHEMBL31751712 | 0.89 | NR1H2 (0.44) | NR1H2GRM5ESR2POLB | |
| SCHEMBL30793510 | 0.83 | NR1H2 (0.40) | NR1H2GRM5ESR2POLB | |
| SCHEMBL12307404 | 0.83 | NR1H2 (0.48) | NR1H2GRM5ESR2POLB | |
| SCHEMBL16682725 | 0.83 | NR1H2 (0.42) | NR1H2GRM5ESR2POLB | |
| SCHEMBL14158771 | 0.82 | NR1H2 (0.47) | NR1H2GRM5ESR2POLB | |
| SCHEMBL18183751 | 0.82 | NR1H2 (0.47) | NR1H2GRM5ESR2POLB | |
| SCHEMBL12307412 | 0.82 | NR1H2 (0.48) | NR1H2GRM5ESR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010333-A1 | PLASMA KALLIKREIN INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2022-06-15 | — | — | EP | disclosed |