Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.71 |
| ▸ | PARP1 | P09874 | 8/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | IP6K1 | Q92551 | 5/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | IP6K3 | Q96PC2 | 3/20 | 0.46 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263292 | 1.00 | SLC2A1 (0.71) | SLC2A1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL31067306 | 0.88 | PARP1 (0.56) | SLC2A1PARP1CHEK1PIM1ALOX15 | |
| SCHEMBL265032 | 0.88 | PARP1 (0.56) | SLC2A1PARP1CHEK1PIM1ALOX15 | |
| SCHEMBL22990268 | 0.86 | SLC2A1 (0.54) | SLC2A1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL2116665 | 0.85 | SLC2A1 (0.66) | SLC2A1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL263154 | 0.81 | SLC2A1 (0.74) | SLC2A1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL2118498 | 0.81 | SLC2A1 (0.68) | SLC2A1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL4179088 | 0.80 | SLC2A1 (0.72) | SLC2A1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL3845750 | 0.80 | SLC2A1 (0.72) | SLC2A1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL30205619 | 0.80 | SLC2A1 (0.72) | SLC2A1PARP1CHEK1PIM1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010334-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | Novartis AG (CH) | 2022-06-15 | — | — | EP | disclosed |