Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19850884 | 1.00 | DYRK1A (0.67) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL28591455 | 0.92 | DYRK1A (0.65) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL29699060 | 0.90 | DYRK1A (0.65) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL18163667 | 0.90 | DYRK1A (0.65) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL15271211 | 0.89 | DYRK1A (0.70) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL18163677 | 0.89 | DYRK1A (0.64) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL29698901 | 0.89 | DYRK1A (0.64) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL18154367 | 0.89 | DYRK1A (0.63) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL15271105 | 0.88 | TSHR (0.77) | DYRK1ATSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL29698933 | 0.87 | DYRK1A (0.67) | DYRK1ATSHRHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| EP-4011870-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING RILUZOLE PRODRUGS | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2022-06-15 | — | — | EP | disclosed |