Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29570778 | 1.00 | DRD1 (0.46) | DRD1NPSR1KMT2AMEN1POLB | |
| SCHEMBL5078882 | 1.00 | DRD1 (0.46) | DRD1NPSR1KMT2AMEN1POLB | |
| SCHEMBL23181343 | 0.93 | DRD1 (0.41) | DRD1NPSR1KMT2AMEN1POLB | |
| SCHEMBL29412647 | 0.92 | DRD1 (0.40) | DRD1NPSR1KMT2AMEN1POLB | |
| SCHEMBL18304637 | 0.92 | DRD1 (0.40) | DRD1NPSR1KMT2AMEN1POLB | |
| SCHEMBL23174129 | 0.90 | DRD1 (0.40) | DRD1NPSR1KMT2AMEN1POLB | |
| SCHEMBL10016845 | 0.89 | DRD1 (0.39) | DRD1NPSR1KMT2AMEN1POLB | |
| SCHEMBL16638799 | 0.89 | DRD1 (0.39) | DRD1NPSR1KMT2AMEN1POLB | |
| SCHEMBL29435775 | 0.87 | DRD1 (0.71) | DRD1NPSR1KMT2AMEN1 | |
| SCHEMBL10154120 | 0.87 | DRD1 (0.71) | DRD1NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023202625-A1 | FGFR2 INHIBITOR AND METHOD FOR USING SAME | 深圳福沃药业有限公司 | 2023-10-26 | — | — | WO | disclosed |
| CN-116903628-A | FGFR2 inhibitors and methods of use | 深圳福沃药业有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-115677684-A | Substituted aryl or heteroaryl compounds | 先声药业有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115315423-A | Substituted aryl compounds | 先声药业有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2022134641-A1 | AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |
| WO-2022134642-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |