Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.71 |
| ▸ | CCNK | O75909 | 19/20 | 0.71 |
| ▸ | CDK9 | P50750 | 19/20 | 0.71 |
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.71 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.71 |
| ▸ | CDK2 | P24941 | 16/20 | 0.71 |
| ▸ | CDK7 | P50613 | 7/20 | 0.71 |
| ▸ | CCNH | P51946 | 7/20 | 0.71 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26627123 | 1.00 | CCNT1 (0.71) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588204 | 0.89 | CCNK (0.84) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588250 | 0.88 | CCNT1 (0.65) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL26627081 | 0.87 | CCNT1 (0.65) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24589041 | 0.87 | CCNT1 (0.65) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL26627189 | 0.87 | CCNT1 (0.65) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588097 | 0.87 | CCNT1 (0.65) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588921 | 0.87 | CCNT1 (0.65) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588923 | 0.87 | CCNT1 (0.65) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588771 | 0.86 | CCNT1 (0.68) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745277-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-09-12 | — | — | CN | disclosed |
| WO-2022134642-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |