Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 17/20 | 0.56 |
| ▸ | CCNK | O75909 | 17/20 | 0.56 |
| ▸ | CDK9 | P50750 | 17/20 | 0.56 |
| ▸ | CDK12 | Q9NYV4 | 17/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 15/20 | 0.56 |
| ▸ | CDK2 | P24941 | 15/20 | 0.56 |
| ▸ | CDK7 | P50613 | 9/20 | 0.56 |
| ▸ | CCNH | P51946 | 9/20 | 0.56 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26627147 | 1.00 | CCNT1 (0.56) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL26627150 | 1.00 | CCNT1 (0.56) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588273 | 0.93 | CCNT1 (0.60) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL26627187 | 0.93 | CCNT1 (0.60) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588775 | 0.93 | CCNT1 (0.62) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588260 | 0.88 | CCNT1 (0.62) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL24588278 | 0.88 | CCNT1 (0.62) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL29699095 | 0.86 | CCNT1 (0.60) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL26627130 | 0.86 | CCNT1 (0.60) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL26627127 | 0.86 | CCNT1 (0.60) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745277-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-09-12 | — | — | CN | disclosed |
| WO-2022134642-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 湃隆生物科技有限公司（香港） | 2022-06-30 | — | — | WO | disclosed |