SCHEMBL2969946

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2966394	0.96	LCK (1.00)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2967784	0.91	KDM4E (0.84)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2975444	0.90	LCK (0.89)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2972462	0.90	KDM4E (0.82)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2968470	0.90	TNK2 (1.00)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2967166	0.87	TNK2 (1.00)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2962922	0.86	LCK (0.85)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2976737	0.86	TNK2 (1.00)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2960951	0.86	TNK2 (1.00)	LCKTNK2KDRJAK3EGFR
	SCHEMBL2966974	0.86	LCK (0.80)	LCKTNK2KDRJAK3EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.