Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 15/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989891 | 0.83 | MAPK1 (0.60) | MAPK1RIPK1AXLCDK8 | |
| SCHEMBL12847281 | 0.75 | MAPK1 (0.71) | MAPK1RIPK1APPAXLNUDT1 | |
| SCHEMBL10141177 | 0.75 | MAPK1 (0.48) | MAPK1RIPK1APPAXLNUDT1 | |
| SCHEMBL2967092 | 0.75 | MAPK1 (0.48) | MAPK1RIPK1APPAXLNUDT1 | |
| SCHEMBL25523673 | 0.75 | MAPK1 (0.44) | MAPK1RIPK1APPAXLNUDT1 | |
| SCHEMBL25207314 | 0.72 | RET (0.41) | MAPK1DYRK1A | |
| SCHEMBL20874821 | 0.72 | MAPK1 (0.41) | MAPK1RIPK1CDK8 | |
| SCHEMBL25934515 | 0.71 | MAPK1 (0.50) | MAPK1RIPK1AXLNUDT1DYRK1A | |
| SCHEMBL20875000 | 0.71 | MAPK1 (0.46) | MAPK1RIPK1APP | |
| SCHEMBL12810052 | 0.71 | MAPK1 (0.44) | MAPK1RIPK1APPAXLNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661557-A | Disubstituted nitrogen-containing five-membered heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2025-03-21 | — | — | CN | claimed |
| EP-3450436-B1 | CONDENSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2022-07-27 | — | — | EP | disclosed |