Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.81 |
| ▸ | CDC7 | O00311 | 5/20 | 0.73 |
| ▸ | PIM1 | P11309 | 3/20 | 0.60 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.60 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.60 |
| ▸ | CLK1 | P49759 | 1/20 | 0.60 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.60 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385542 | 1.00 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL28544732 | 0.90 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL19782845 | 0.86 | CDC7 (0.76) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL385565 | 0.84 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL28539861 | 0.84 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL383396 | 0.81 | CDC7 (0.72) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL22026472 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL384812 | 0.81 | KDM4E (0.74) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL383305 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL385834 | 0.79 | CDC7 (0.72) | KDM4EALDH1A1HPGDHSD17B10CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220170904-A1 | SYSTEMS AND METHODS FOR MONITORING BIOLOGICAL TISSUE DEGRADATION | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-06-02 | — | — | US | disclosed |