Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 6/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10592361 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL7997152 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL7780283 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL8713351 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL1585944 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL17309672 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11469243 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL8430973 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11309619 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL9135671 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879597-A | Antibacterial red glaze ceramic cup and preparation method thereof | 淄博丰之源贸易有限公司 | 2019-06-14 | — | — | CN | claimed |
| CN-108969503-A | Multivitamin effervescent tablet and preparation method thereof | 江苏汉典生物科技股份有限公司 | 2018-12-11 | — | — | CN | claimed |
| CN-108862455-A | A kind of river wastewater inorganic agent | 四川盈乾建设工程有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108643882-A | A kind of H in crude oil2The removing method of S | 西安凯尔文石化助剂制造有限公司 | 2018-10-12 | — | — | CN | claimed |
| CN-108193245-A | The compound zinc-plated production technology of steel pipe | 荆大（荆州）汽车配件股份有限公司 | 2018-06-22 | — | — | CN | claimed |
| CN-108118196-A | A kind of preparation method of aluminium manganese intermediate alloy | 南通昂申金属材料有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-107758881-A | A kind of preparation method of sewage flotation antisludging agent | 南京悠谷新材料科技有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-107572668-A | A kind of sewage disposal formula of good purification | 四川行之智汇知识产权运营有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-107384648-A | A kind of germicidal soaps | 安庆华威油脂科技有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-107118874-A | A kind of multifuctional cleaning agent | 滕晓明 | 2017-09-01 | — | — | CN | claimed |
| CN-104862022-A | Automobile exhaust purifying agent and preparation method thereof | DU XIAOWEI | 2015-08-26 | — | — | CN | claimed |
| CN-104233357-A | Stainless steel machinery equipment cleaning agent and preparation method thereof | JURONG JINGHOU MACHINERY RES INST CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-104194523-A | External wall paint containing bentonite | SUZHOU LUOTELAN NEW MATERIAL TECHNOLOGY CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-103318578-B | Forming method of large-scale metal storage tank with high bonding strength inner wall anticorrosive layer | WUXI XINKAIHE TANK CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-104071881-A | Flocculating agent for waste water treatment, and preparation method thereof | LIAN YONG | 2014-10-01 | — | — | CN | claimed |
| CN-103994460-A | Feeding method and device for synergistically handling household garbage by adopting cement kiln | CHINA LIGHT INDUSTRY NANNING DESIGN ENG CO LTD | 2014-08-20 | — | — | CN | claimed |
| CN-103876181-A | Preparation method of preserved duck eggs | WANG YAO | 2014-06-25 | — | — | CN | claimed |
| CN-103668238-A | Environment-friendly microorganism degreasing agent | ZHANG JINBI | 2014-03-26 | — | — | CN | claimed |
| CN-103125523-A | Weeding pesticide | JIANGSU ZISHI CHEMICAL TECHNOLOGY CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-102715188-A | Aquiculture disinfection powder and preparation method thereof | WUXI QIAOYOU TECHNOLOGY CO LTD | 2012-10-10 | — | — | CN | claimed |