Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | CETP | P11597 | 3/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908642 | 0.83 | TSHR (1.00) | TSHRCETPSRCFOLH1PDPK1 | |
| SCHEMBL51316 | 0.83 | TSHR (1.00) | TSHRCETPSRCFOLH1PDPK1 | |
| SCHEMBL9446520 | 0.81 | TSHR (0.96) | TSHRCETPSRCFOLH1PDPK1 | |
| Hydrochloric Acid SCHEMBL10722992 | 0.81 | TSHR (0.96) | TSHRCETPSRCFOLH1PDPK1 | |
| SCHEMBL4219700 | 0.81 | TSHR (0.96) | TSHRCETPSRCFOLH1PDPK1 | |
| Ammonia Solution, Strong SCHEMBL7268743 | 0.81 | TSHR (0.96) | TSHRCETPSRCFOLH1PDPK1 | |
| Phosphoric Acid SCHEMBL27741297 | 0.81 | TSHR (0.96) | TSHRCETPSRCFOLH1PDPK1 | |
| SCHEMBL11756554 | 0.81 | TSHR (0.96) | TSHRCETPSRCFOLH1PDPK1 | |
| SCHEMBL28264490 | 0.81 | TSHR (0.96) | TSHRCETPSRCFOLH1PDPK1 | |
| SCHEMBL28032525 | 0.81 | TSHR (0.96) | TSHRCETPSRCFOLH1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114616225-A | Treprostinil prodrugs | 联合治疗公司 | 2022-06-10 | — | — | CN | disclosed |